What is orlistat?


The subject of slimming, especially the ladies, because this topic is a topic always on the agenda, which is used in another drug, Xenical®(orlistat) I wanted to mention. First, in April 1999 the FDA approved the use of these drugs for the purpose of slimming. The mechanism of action of this drug to prevent the absorption of fats in the digestive system shaped. This is the breakdown of fats in the digestive system, which enables “lipase” enzyme called preventing the operation. Thus, large molecular structures in foods we eat, oils (triglycerides) into fatty acids suitable for the absorption of does not translate. Blocked absorption of fats and the excretion increased by 30%. 

Orlistatin the continuity of current weight weight loss re-gaining weight and obesity-related effects on the number of disease as I have 7 working. In these studies, patients receiving orlistat compared with placebo treatment patients were treatment area 2800 1400. All patients during the study period, 20% low-calorie and 30% fat diet they received. In addition, they were informed that all patients in terms of their diet. Research from patients who have completed 1 year at the end of treatment in the orlistat group that uses 57% In the placebo group, 30% of their initial weight by at least 5% Weight lost.
The FDA suggests that a drug be taken with a meal that contains fat in capsule form. But patients where application is required of a good diet, low calories and food intake it is necessary to more than 30% of the fat should not contain strongly indicated. Body-mass index (body mass index, BMI = weight/(Height)2) individuals and those with high cholesterol, which is the index if it goes above 30 or above 27, it is stated that those with hypertension or those with diabetes can use. Side effects especially on the gastrointestinal system (see Fig. Orlistat about two questions and two answers...). But as systemic fat absorbed vitamins (A, D, E, K) by decreasing the absorption of side effects. It should be noted that may cause drug interactions. 

In another report published in February 2007, the FDA orlistat OTC medications (over-the-counter Use = over-the-counter medications or over-the-counter medicines) the Group took. But especially those with absorption problems in the digestive system, organ transplant recipients, thyroid disease, like diabetes, with long-term patients, drug before using this medication, your physician declared that he should meet with. 

Farmville note: excess weight is dangerous, but uncontrolled drug use more dangerous.